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Contents: March 2012, Volume 2012, Issue 1   [Index by Author]       Educational Sessions        Targeting the Androgen Receptor for Prostate Cancer Prevention and Therapy        Cancer Signaling        Molecular and Systems Pathology in Human Cancer        Nutritionally Based Cancer Risk Reductive Interventions        The Hypoxic Tumor Microenvironment as a Target for Cancer Therapy        Cancer Vaccines        Myelodysplastic Syndromes: New Pathways and Treatment        Prostate Cancer Mouse Models        Targeting the Epigenome to Treat Cancer        The Role of Infectious Agents in Cancer        Understanding Cancer Metabolism Pathways        Cancer Stem Cells: New Insights from New Approaches        Current Challenges in Molecular Marker Research        Melanoma: Moving beyond BRAF        Targeting the p53 Tumor Suppressor Pathway in Cancer Therapy        Chemical Strategies for Modulating Protein-Protein Inhibition        Molecular Pathology of B-Cell Neoplasia      Methods Workshops        Modeling Pediatric Malignancy        'Seq'ing the Future of Cancer        Molecular Imaging        Phase II Trials: Are We Asking Too Much?        Omics Approach to Adaptive Clinical Trials

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Educational Sessions

Targeting the Androgen Receptor for Prostate Cancer Prevention and Therapy

Marianne D. Sadar

Advances in Androgen Receptor Antagonists
Am Assoc Cancer Res Educ Book 2012: 3-7. doi: 10.1158/AACR.EDB-12-8402. [Full Text] [PDF]  

William C. Krause and Nancy L. Weigel

Cross-talk between Androgen Receptors and Cell Signaling Pathways in Prostate Cancer
Am Assoc Cancer Res Educ Book 2012: 9-13. doi: 10.1158/AACR.EDB-12-8404. [Full Text] [PDF]  

Cancer Signaling

Verline Justilien and Alan P. Fields

Atypical Protein Kinase C Signaling in Cancer
Am Assoc Cancer Res Educ Book 2012: 17-22. doi: 10.1158/AACR.EDB-12-8421. [Full Text] [PDF]  

Marcelo G. Kazanietz

PKC and Cancer: Time for a Comeback?
Am Assoc Cancer Res Educ Book 2012: 23-26. doi: 10.1158/AACR.EDB-12-8423. [Full Text] [PDF]  

Molecular and Systems Pathology in Human Cancer

Ila R. Singh

Viruses and Cancer
Am Assoc Cancer Res Educ Book 2012: 29-30. doi: 10.1158/AACR.EDB-12-8539. [Full Text] [PDF]  

Janina A. Longtine

Molecular Genetics of Adult Myeloid Leukemia
Am Assoc Cancer Res Educ Book 2012: 31-32. doi: 10.1158/AACR.EDB-12-8466. [Full Text] [PDF]  

Julide Tok Celebi

Molecular Genetics of Melanoma
Am Assoc Cancer Res Educ Book 2012: 33-34. doi: 10.1158/AACR.EDB-12-8468. [Full Text] [PDF]  

Carlos Cordon-Cardo

Molecular and Systems Pathology in Prostate Cancer
Am Assoc Cancer Res Educ Book 2012: 35-36. doi: 10.1158/AACR.EDB-12-8965. [Full Text] [PDF]  

Nutritionally Based Cancer Risk Reductive Interventions

William P. Steward

Dietary Interventions and Use of Diet-Derived Agents as Chemopreventives to Reduce Cancer Risk
Am Assoc Cancer Res Educ Book 2012: 39-43. doi: 10.1158/AACR.EDB-12-8578. [Full Text] [PDF]  

The Hypoxic Tumor Microenvironment as a Target for Cancer Therapy

Juri G. Gelovani

Hypoxia and Radiation Resistance: The Role of HIF1α Signaling and Stromal Adaptation
Am Assoc Cancer Res Educ Book 2012: 47-51. doi: 10.1158/AACR.EDB-12-1658. [Full Text] [PDF]  

Adrian L. Harris and Dylan T. Jones

Current Clinical Strategies for Targeting Hypoxic Cancer Cells
Am Assoc Cancer Res Educ Book 2012: 53-58. doi: 10.1158/AACR.EDB-12-1656. [Full Text] [PDF]  

Cancer Vaccines

Carl G. Figdor, Gerty Schreibelt, and I. Jolanda M. de Vries

Novel Concepts in Dendritic Cell Vaccination against Cancer
Am Assoc Cancer Res Educ Book 2012: 61-65. doi: 10.1158/AACR.EDB-12-8406. [Full Text] [PDF]  

Sacha Gnjatic

A Stepwise Approach to the Development of Cancer Vaccines
Am Assoc Cancer Res Educ Book 2012: 67-71. doi: 10.1158/AACR.EDB-12-8545. [Full Text] [PDF]  

Myelodysplastic Syndromes: New Pathways and Treatment

Michaëla Fontenay

Heterogeneous Genotypes Support Common Phenotypic Features in Myelodysplastic Syndromes
Am Assoc Cancer Res Educ Book 2012: 75-79. doi: 10.1158/AACR.EDB-12-2567. [Full Text] [PDF]  

Seishi Ogawa

Deregulated RNA Splicing Machinery in Myelodysplastic Syndromes
Am Assoc Cancer Res Educ Book 2012: 81-85. doi: 10.1158/AACR.EDB-12-2571. [Full Text] [PDF]  

Prostate Cancer Mouse Models

Simon W. Hayward

Studying Epithelial-Stromal Interactions in Prostate Cancer Using Tissue Recombination Models
Am Assoc Cancer Res Educ Book 2012: 89-94. doi: 10.1158/AACR.EDB-12-6303. [Full Text] [PDF]  

Eva Corey

Human Prostate Cancer Xenograft Models: Use in Studies of Biology of Prostate Cancer and Preclinical Testing
Am Assoc Cancer Res Educ Book 2012: 95-99. doi: 10.1158/AACR.EDB-12-6309. [Full Text] [PDF]  

Brett S. Carver

Preclinical Studies of Drug Response Using Genetically Engineered Mouse Models of Prostate Cancer
Am Assoc Cancer Res Educ Book 2012: 101-104. doi: 10.1158/AACR.EDB-12-6317. [Full Text] [PDF]  

Targeting the Epigenome to Treat Cancer

Victoria M. Richon, Mikel P. Moyer, and Robert A. Copeland

Protein Methyltransferases as Targets for Personalized Cancer Therapeutics
Am Assoc Cancer Res Educ Book 2012: 107-112. doi: 10.1158/AACR.EDB-12-2193. [Full Text] [PDF]  

Mark A. Dawson

Epigenetic Regulators in Cancer
Am Assoc Cancer Res Educ Book 2012: 113-116. doi: 10.1158/AACR.EDB-12-4133. [Full Text] [PDF]  

The Role of Infectious Agents in Cancer

Sankar Swaminathan

Epstein-Barr Virus: A Spectrum of Disease from Mononucleosis to Lymphoma
Am Assoc Cancer Res Educ Book 2012: 119-122. doi: 10.1158/AACR.EDB-12-8378. [Full Text] [PDF]  

Understanding Cancer Metabolism Pathways

Georgia Hatzivassiliou

Targeting Metabolism for Cancer Therapy
Am Assoc Cancer Res Educ Book 2012: 125-128. doi: 10.1158/AACR.EDB-12-7337. [Full Text] [PDF]  

Cancer Stem Cells: New Insights from New Approaches

A.G. Turhan

Chronic Myeloid Leukemia Stem Cells: Lessons from a Lead Paradigm
Am Assoc Cancer Res Educ Book 2012: 131-135. doi: 10.1158/AACR.EDB-12-1562. [Full Text] [PDF]  

Current Challenges in Molecular Marker Research

Daniel F. Hayes, Lisa Mcshane, and David Ransohoff

A Bad Tumor Marker Is as Bad as a Bad Drug: Applying Scientific Principles to Tumor Biomarker Research
Am Assoc Cancer Res Educ Book 2012: 139-141. doi: 10.1158/AACR.EDB-12-8432. [Full Text] [PDF]  

Melanoma: Moving beyond BRAF

Michael A. Davies

Targeting the PI3K-AKT Pathway in Melanoma
Am Assoc Cancer Res Educ Book 2012: 145-150. doi: 10.1158/AACR.EDB-12-1605. [Full Text] [PDF]  

Keiran S. M. Smalley

Beyond BRAF: Targeting Ras in Melanoma
Am Assoc Cancer Res Educ Book 2012: 151-154. doi: 10.1158/AACR.EDB-12-1607. [Full Text] [PDF]  

Scott Woodman

KIT Mutations in Melanoma: Where Are We Now?
Am Assoc Cancer Res Educ Book 2012: 155-159. doi: 10.1158/AACR.EDB-12-1609. [Full Text] [PDF]  

Boris C. Bastian

Somatic Genetic Alterations in Melanoma: Implications for Diagnosis, Classification, and Therapy Stratification
Am Assoc Cancer Res Educ Book 2012: 161-162. doi: 10.1158/AACR.EDB-12-1611. [Full Text] [PDF]  

Targeting the p53 Tumor Suppressor Pathway in Cancer Therapy

James J. Manfredi

The p53 Tumor Suppressor Pathway in Tumorigenesis and Therapy
Am Assoc Cancer Res Educ Book 2012: 165-169. doi: 10.1158/AACR.EDB-12-6392. [Full Text] [PDF]  

David P. Lane and Chit Fang Cheok

p53 Pathway and Cancer Therapy
Am Assoc Cancer Res Educ Book 2012: 171-176. doi: 10.1158/AACR.EDB-12-6400. [Full Text] [PDF]  

Chemical Strategies for Modulating Protein-Protein Inhibition

Guowei Fang

Targeting Protein-Protein Interactions in Oncology
Am Assoc Cancer Res Educ Book 2012: 179-182. doi: 10.1158/AACR.EDB-12-8601. [Full Text] [PDF]  

Molecular Pathology of B-Cell Neoplasia

Randy D. Gascoyne

The Molecular Pathogenesis of Follicular Lymphoma
Am Assoc Cancer Res Educ Book 2012: 185-190. doi: 10.1158/AACR.EDB-12-2267. [Full Text] [PDF]  

Sami N. Malek

Chronic Lymphocytic Leukemia: An Update
Am Assoc Cancer Res Educ Book 2012: 191-195. doi: 10.1158/AACR.EDB-12-7272. [Full Text] [PDF]  

P. Leif Bergsagel

Molecular Mechanisms of Mature B-Cell Neoplasia: Multiple Myeloma
Am Assoc Cancer Res Educ Book 2012: 197-201. doi: 10.1158/AACR.EDB-12-2576. [Full Text] [PDF]  

Methods Workshops

Modeling Pediatric Malignancy

Lara Davis and Charles Keller

Integrative Biology of Rhabdomysarcoma Using Genetic Murine Models
Am Assoc Cancer Res Educ Book 2012: 205-209. doi: 10.1158/AACR.EDB-12-8540. [Full Text] [PDF]  

'Seq'ing the Future of Cancer

Ting Wang

The Modern Cancer Methylomics: Genome-wide DNA Methylation Analysis
Am Assoc Cancer Res Educ Book 2012: 213-217. doi: 10.1158/AACR.EDB-12-8272. [Full Text] [PDF]  

Molecular Imaging

Anna M. Wu

Engineered Antibodies for Rapid Clinical Imaging of Cell Surface Markers
Am Assoc Cancer Res Educ Book 2012: 221-225. doi: 10.1158/AACR.EDB-12-8227. [Full Text] [PDF]  

A.G.T. Terwisscha van Scheltinga, L.E. Lamberts, J.R. de Jong, A.H. Brouwers, M.N. Lub-de Hooge, and E.G.E. de Vries

Molecular Imaging of Tumors with Radioactive Labeled Antibodies from Laboratory to the Clinic
Am Assoc Cancer Res Educ Book 2012: 227-232. doi: 10.1158/AACR.EDB-12-8229. [Full Text] [PDF]  

Phase II Trials: Are We Asking Too Much?

Gary M. Clark

The Dangers of Underpowered Phase II Clinical Trials
Am Assoc Cancer Res Educ Book 2012: 235-239. doi: 10.1158/AACR.EDB-12-8309. [Full Text] [PDF]  

Omics Approach to Adaptive Clinical Trials

Donald A. Berry, Laura J. Esserman, Joe W. Gray, and Laura van 't Veer

"-Omics" Approach to Adaptive Clinical Trials
Am Assoc Cancer Res Educ Book 2012: 243-249. doi: 10.1158/AACR.EDB-12-8338. [Full Text] [PDF]  

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